Preliminary study on virtual touch tissue quantification for evaluation of small focal liver lesions
10.3760/cma.j.issn.1004-4477.2013.01.009
- VernacularTitle:声触诊组织量化技术对肝局灶性小病变定性诊断价值的初步研究
- Author:
Zhifang ZHONG
;
Jianhua CUI
;
Xingtian WANG
;
Rong WANG
;
Peipu SHEN
;
Meimei WEI
;
Dujuan XU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Liver diseases;
Virtual touch tissue quantification
- From:
Chinese Journal of Ultrasonography
2013;(1):34-37
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the application value of virtual touch tissue quantification (VTQ)for evaluating small focal liver lesions.Methods Seventy-seven patients with 89 small focal liver lesions,whose largest diameter were less than or equal to 3 cm were evaluated with VTQ.The shcar wave velocity (SWV) of the tumor and background liver parenchyma were calculated,and their results were compared with those of 40 healthy subjects.Statistical analysis was performed on the SWV for the differentiation of normal liver,background liver parenchyma and lesions.The cut-off point for SWV was obtained by using ROC curve analysis which was used to predict malignancy lesions.Results The SWV of malignant lesions was significantly higher than that of benign ones [(2.56-± 0.67) m/s vs (1.70 ± 0.55) m/s,P =0.000].The SWV of metastatic liver carcinoma which came from lung cancer and breast cancer were higher than that of gastrointestinal tract cancer transfers (P =0.000).Based on 1.93 m/s as the cut-off point of SWV value,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value for diagnosing malignancies were 82.0 ％,84.6％,83.15 ％,87.23 ％ and 78.57 ％ respectively.Conclusions VTQ technique can help the differential diagnosis of small focal liver lesions.
