Virtual touch tissue imaging in the differential diagnosis of small solid thyroid nodules
10.3760/cma.j.issn.1004-4477.2013.02.013
- VernacularTitle:声触诊组织成像鉴别甲状腺实性小结节的应用价值
- Author:
Xingtian WANG
;
Rong WANG
;
Xingrong ZHANG
;
Zhifang ZHONG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Thyroid nodule;
Diagnosis,differential;
Virtual touch tissue imaging
- From:
Chinese Journal of Ultrasonography
2013;(2):133-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of virtual touch tissue imaging (VTI) in the differential diagnosis of small solid thyroid nodules.Methods 35 patients with 41 small thyroid nodules were examined by conventional ultrasound and VTI examination.The stiffness of the nodules in VTI images was scored.Area ratios of VTI and gray scale images of nodules were calculated.The pathological diagnosis was used as the gold standard.The ROC curve was drawn to determine the cut off point of area ratio to predict thyroid cancer.Results 41 small thyroid nodules were confirmed by pathological diagnosis,including 23 benign and 18 malignant nodules.Compared with benign nodules,the ratio of VTI hardness score ≥4 was significantly higher in the malignant nodules (88.9％ vs 8.7％,P ＜0.01).Compared with benign nodules,the area ratios of malignant nodules were higher (1.67 ± 0.16 vs 1.23 ± 0.12,P ＜0.01).When 1.46 was set as the cut off point of areas ratio,the sensitivity and specificity of diagnosing thyroid cancer were 88.9％ and 95.7％,respectively.Conclusions VTI can provide information about thyroid nodules hardness.It has high value in the differential diagnosis of small solid thyroid nodules.
