Application value of contrast-enhanced ultrasound combined with time-intensity curve to identify benign and malignant orbital neoplasms
10.3760/cma.j.issn.1004-4477.2013.01.021
- VernacularTitle:超声造影时间－强度曲线在眼眶良恶性肿瘤鉴别诊断中的应用价值
- Author:
Gang BAI
;
Wenwei CHEN
;
Bin SUN
;
Liao CHEN
;
Ying KANG
;
Ji CHEN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Orbital neoplasms
- From:
Chinese Journal of Ultrasonography
2013;(1):63-66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of ultrasound-enhanced ultrasound (CEUS) in the differential diagnosis of orbital neoplasms by observing the perfusion characteristics of orbital benign and malignant neoplasms for the application of ultrasound contrast microbubbles.Methods Preoperative ultrasound imaging of 47 patients with orbital neoplasms(benign group 35 cases,malignant group 12 cases)were observed for the tumor characteristics of CEUS.The parameters of tumor imaging obtained time intensity curve (TIC) were obtained by quantitative analysis of SonoLiver analysis software,which were contrast agent arrive time (AT),rise time (RT),time to peak (TTP),mean transit time (mTT),area under the curve (AUC),maximum intensity(IMAX) and perfusion index (PI).Results Different characteristics of perfusion were shown between benign and malignant groups.Time parameters of TIC:rising slope,semidescending slope,IMAX,PI,mTT,semi-washed out time and RT were significantly different between the two groups (P ＜ 0.05) while there was no significant difference of parameters as AT,TTP,AUC.Conclusions There is certain clinical value of the CEUS in the differential diagnosis of ocular benign and malignant neoplasms.
