Study of high intensity focused ultrasound in cervix intraepitheliar neoplasia grade Ⅰ prognosis
10.3760/cma.j.issn.1004-4477.2013.01.015
- VernacularTitle:轻度宫颈上皮内瘤样病变高强度聚焦超声治疗的转归研究
- Author:
Wei ZHANG
;
Demin CHENG
;
Yanqiu ZHOU
;
Ying LIU
;
Changhuai ZHANG
;
Jianxin ZHANG
;
Ruifang WU
- Publication Type:Journal Article
- Keywords:
Ultrasound,high intersity focused;
Cervical intraepithelial neoplasia;
Prognosis
- From:
Chinese Journal of Ultrasonography
2013;(1):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness of cervical intraepitheliar neoplasia grade Ⅰ (CIN Ⅰ) after treated by high intensity focused ultrasound (HIFU) Ⅰ.Methods 155 CIN Ⅰ cases in treatment group started following after HIFU method,548 cases in control group started following after cervical biopsy under the colposcope.The following intermissions were 6 months,12 months,24 months,36 months,Liquid based cytological test (LCT) and hybrid captured-Ⅱ for high rate-humanpapilomavirus (HR-HPV)test were used in every following test,and if the LCT result was atypical squamous cells (ASC-US) and HR-HPV positive,or the LCT result was greater than or equal,cervical biopsy was undergone by the colposcope to make sure the CIN Ⅰ diagnosis.Results (1) The lost rates of treatment group and control group in 36 months were 18.66％ and 10.22％.(2) The inversion rates in 6 months,12 months,24 months and 36 months were 77.51 ％,80.38 ％,86.12 ％ and 88.28 ％,inversion cases were rose up by the treatment gradually,succession rates were 33.01 ％,22.97％,9.33％ and 1.44％,and descended down gradually.(3)The inversion rates in treatment group and control group increased with observation time,there were significant differences during the 6 months,12 months,24 months and 36 months (P ＜ 0.05) ; the succession rates in treatment group and control group descended with observation time,there were significant differences during the 6 months,12 months and 24 months (P ＜ 0.05),and there were not significant differences in the 36 months,but significant differences between treatment group's and control group s progressive rate.Conclusions No solid scar,improving lesions inversion,reducing succession rate,guarding against the canceration were the advantages of HIFU in treatment for CIN I.
