Characteristics of opportunistic infection in hospitalized acquired immunodeficiency syndrome patients
10.3760/cma.j.issn.1000-6680.2013.02.009
- VernacularTitle:首次住院艾滋病患者机会性感染的特点
- Author:
Li LIU
;
Renfang ZHANG
;
Yinzhong SHEN
;
Yufang ZHENG
;
Hongzhou LU
- Publication Type:Journal Article
- Keywords:
Acquired immunodeficiency syndrome;
Inpatients;
Superinfection;
Retrospective studies
- From:
Chinese Journal of Infectious Diseases
2013;(2):97-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of opportunistic infections in acquired immunodeficiency syndrome (AIDS) patients.Methods A comprehensive retrospective chart review study was conducted of 603 AIDS patients with different opportunistic infections in a special hospital authorized for AIDS patients.Results In all 603 patients,327 cases (54.2%) were infected with Pneumocystisjiroveci,251 cases (41.6%) were infected with fungus and 210 cases (34.8%) were infected with mycobacterium.Totally 367 cases (60.9%) had only one pathogen and 236 cases (39.1%) were co-infected with more than one pathogen.A total of 390 cases (64.7%) had a single site of infection with the respiratory tract being most frequently involved (271 cases,69.5%),and 213 cases (35.3%) had more than one infected site.The most common coinfected sites were oropharynx and respiratory tract (111 cases,52.1%).Conclusions AIDS patients are usually coinfected with multiple pathogenic organisms and multi-systems involved.Most of the opportunistic infections can be cured by timely diagnosis and effective treatment to prolong life and improve the quality of life of AIDS patients.