The clinical study of citalopram on affective disorder after cerebral infarction
10.3760/cma.j.issn.1674-6554.2013.02.015
- VernacularTitle:西酞普兰治疗脑梗死后病理性哭泣的临床疗效
- Author:
Xuhua YI
;
Jun LONG
;
Lijuan LIU
;
Junlei YIN
;
Junfeng GUO
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Pathological crying;
Treatment;
Citalopram
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2013;(2):144-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate efficacy of citalopram on pathological crying after cerebral infarction.Methods 106 patients with pathological crying after cerebral infarction were randomly divided into two groups,treatment group(54 cases) and control group(52 cases).Control group received conventional treatment of cerebrovascular disease.Treatment group taken citalopraml0-20mg orally one time per day for three months based on conventional treatment.The total response rate,effectual time,and Hasegawa Dementia Scale (HDS) scores were compared between two groups after treatment.Results There were significant differences in total response rates (94.4％ and 38.5％,respectively),effectual time(1.98 ± 1.24 and 78 ± 17.95,respectively) and HDS(8.43 ±2.21 and 6.24 ±2.02,respectively) between treatment group and control group (P ＜ 0.01).Conclusion The study suggests that it is effective to treat pathological crying with citalopram and its effect is quick.Citalopram can not only control patient’s pathological crying,but also improve cognitive function.
