Application of homocysteine, serum high sensitive C-reactive protein, lipoprotein A and D-two dimer combined detection in the course of coronary heart disease
10.3760/cma.j.issn.1008-6706.2013.06.028
- VernacularTitle:冠心病患者血清同型半胱氨酸、超敏C反应蛋白、脂蛋白(a)及D-二聚体联合检测的意义
- Author:
Zhenyong QI
;
Junli GE
;
Zhenshui QI
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Homocysteine;
C-reactive protein;
Lipoprotein (a);
D-two dimer
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(6):860-862
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the meaning of Homocysteine,serum high sensitive C-reactive protein,lipoprotein A and D-two dimer combined detection in the course of coronary heart disease.Methods Select 180 cases suffering from different types of coronary heart disease as group of coronary heart disease,200 healthy people who were in our hospital physical examination qualified over the same period as the control group,all the cases of fasting venous blood was sampled respectively to detect the content of Hcy,hs-CRP,LP(a) and DD.Results Coronary heart disease group of patients with Hcy,hs-CRP,LP(a) and DD levels were significantly higher than those of the control group of healthy persons(t =13.87,10.24,9.86,18.02,P < 0.05),Comparison among different indicators of the patiens with Coronary heart disease:the group of AMI was higher than the group of UAP (t =15.79,9.73,11.47,17.34,all P < 0.05),the group of UAP was higher than the group of SAP (t =16.82,8.14,10.65,18.27,P <0.05),the group of SAP was higher than the group of SMI (t =14.36,10.35,9.98,16.52,P < 0.05).Conclusion Monitoring of Hcy,hs-CRP,LP(a) and DD for coronary heart disease,contributes to the understand of the development of the course of coronary heart disease and assess the risk of coronary heart disease.