Investigation on the clinical curative effect and mechanism of four grinding soup oral liquid in treating pediatric indigestion
10.3760/cma.j.issn.1008-6706.2013.05.022
- VernacularTitle:四磨汤口服液治疗小儿消化不良的临床疗效观察及作用机制探讨
- Author:
Huan QIAN
- Publication Type:Journal Article
- Keywords:
Four grinding Soup;
Pediatric indigestion;
Clinical curative effect;
Mechanism of action
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(5):693-695
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and explore the clinical curative effect and mechanism of four grinding soup oral liquid in treating pediatric indigestion.Methods 90 children with indigestion were randomly divided into control group and observation group,and 45 people in each group.Children in control group were given Pan Li ketone tablet and the observation group were given four grinding soup oral liquid to observe the clinical curative effect of the two groups and gastric emptying function,symptoms and plasma substance P,motilin levels of patients before and after treating.Results The clinical efficient of Pan Li ketone tablet and four grinding soup oral liquid were 70.0% and 94.0% respectively.The total effective rate of tgastric emptying of the control group and observation group of were 74.0% and 80.0%,and there were no significant difference (P > 0.10).The plasma substance P,and motilin content of the two groups before and after treatment had significant difference(P < 0.05),but there was no significant difference (P > 0.05) between group after treating; Conclusion Four Grinding Soup oral liquid is a safe and effective way in treating pediatric indigestion,and it can promote gastric emptying function,plasma substance P and motilin levels,which provides certain reference significance for treating clinical indigestion.