Comparison of the effect between zinc distribution of particles and acetaminophen in the treatment of pediatric fever
10.3760/cma.j.issn.1008-6706.2013.03.030
- VernacularTitle:锌布颗粒与对乙酰氨基酚治疗小儿发热的疗效比较
- Author:
Shaonan SHEN
- Publication Type:Journal Article
- Keywords:
Zinc distribution of particles;
Acetaminophen;
Fever;
Child
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(3):389-391
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect of zinc distribution of particles and acetaminophen treats pediatric fever.Methods 108 children with fever were randomly divided into the observation group and the control group,54 cases in each group.The control group was given paracetamol,the observation group was given cloth compound of zinc particles.Efficacy of temperature changes,seizures and the incidence of adverse reaction were compared in two groups.Results The total effective was 96.30％ (52/54) in the observation group,the control group was 81.48％ (44/54),there were no significant differences (x2 =5.86,P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for 0.5h in the observation group (P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for lh in the control group (P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for 0.5,1,2,4 h in the observation group which were lower than those of the control group (P ＜0.05).The incidence of adverse reactions was 12.96％ (7/54) in the control group,which was 11.11％ (6/54) in the observation group,there were no significant differences (P ＞ 0.05).The convulsion rate ioas 3.70％ (2/54) in the observation group,which was 14.81％ (8/54) in the control group,there were no significant differences (P ＜0.05).Conclusion It is faster,longer duration,seizure occurs at a low rate for the cloth compound of zinc particles treats pediatric fever than acetaminophen antipyretic.It is worthy of clinical application.
