Influence of hydroxyethylstarch 200/0.5 on hemodynamic and coagulation in hemodilution for paediatrics patients

VernacularTitle:羟乙基淀粉200/0.5用于血液稀释对小儿血流动力学及凝血功能的影响
Author: Tao ZHU
Publication Type:Journal Article
Keywords: Hetastarch; Sodium lactate; Hemodilution; Central venous pressure; Erythrocyte indices; Partial thromboplastin time; Fibrinogen; International normalized ratio; Child
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(7):979-981
CountryChina
Language:Chinese
Abstract: Objective To study the influence of hydroxyethylstarch 200/0.5 on hemodynamic and coagulation in hemodilution for paediatrics patients(AHH).Methods 64 paediatrics patients who would receive AHH were selected.All patients were randomly divided into HES group(received HES 200/0.5)and control group(received sodium lactate Ringer's),32 patients in each group.Hemodynamic efficacy and coagulation indexes were recorded before AHH(T0),30 min post-AHH(T1) and 60 min post-AHH(T2).Results There were no sinificant differences in MAP,HR,CVP,INR,APTT,CT and FIB compared with T0 or between groups.RBC,Hct and Hb were significantly lower compared with T0,but no significant differences were observed between groups.CI and PT were significantly higher compared with T0,but no significant differences were observed between groups.Conclusion There were no negative effects on hemodynamic efficacy and coagulation in paediatrics patients treating with HES 200/0.5.