Study on risk factors for ventilator associated pneumonia in ICU and pathogens antimicrobial resistance
10.3760/cma.j.issn.1008-6706.2013.03.005
- VernacularTitle:呼吸机相关性肺炎危险因素分析及病原菌耐药性检测
- Author:
Jin LIU
;
Yang LIU
;
Jingjing ZHANG
;
Minghua ZHANG
;
Ying JIN
- Publication Type:Journal Article
- Keywords:
Pneumonia,ventilator;
Risk factors;
Opportunistic infections;
Drug resistance,bacterial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(3):331-333
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the risk factors for ventilator associated pneumonia (VAP) in ICU and pathogens antimicrobial resistance.Methods 220 patients were selected and divided into observation group (88 patients) and control group(132 patients) depending on whetherhe has VAP or not.The clinical data were reviewed to explore the risk factors.And the secretions of respiratory tract were investigated by the routine bacterial culture and drag-resistance methods to analysis the distribution of pathogens.Results The risk factors associated with VAP were COPD,mechanical ventilation,the extensive use of antibiotics,age ＞ 60 years,APACHEII score ＞ 30(P ＜ 0.01).157 bacterial were cultured,68.9％ of pathogens was Gram-negative bacteria in which Pseudomonas aeruginosa was rated as the top one,and 26.1％ of pathogens was Gram-positive bacteria in which MRSA was the majority.The results of the antibiotic resistance monitoring indicated that all Gram-positive and Gram-negative bacteria showed high drugresistance to common antibiotics.Conclusion We should control these risk factors which are closely related to VAP,and select suitable antibiotics on the basis of etiological analysis and drug-resistance.
