Clinical effect of Ginkgo biloba extract combined with Nimodipine on patients with acute cerebral infarction

VernacularTitle:银杏叶提取物联合尼莫地平治疗急性脑梗死疗效观察
Author: Lu SHEN
Publication Type:Journal Article
Keywords: Brain infarction; Ginkgo biloba extract; Nimodipine
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(6):840-842
CountryChina
Language:Chinese
Abstract: Objective To observe the efficacy and safety of Ginkgo biloba extract combined with Nimodipine on patients with acute cerebral infarction.Methods 106 cases of acute cerebral infarction were randomly divided into two groups(control group and treatment group),the control group was given Nimodipine on the basis of regular treatment,and the treatment group was given Ginkgo biloba extract combined with Nimodipine on the basis of regular treatment.Results The total effective rate of treatment group was higher than that of the control group (x2 =3.62,P ＜0.05),improvement of neurological deficit was better than that of the control group (t =2.57,5.32,all P ＜ 0.05),Plasma TC and TG levels were significantly lower than that of the control group(t =4.23,6.43,all P ＜ 0.05).During treatment,patients had no serious adverse reactions.Conclusion Ginkgo biloba extract and Nimodipine have synergistic effects,the two combined treatment of acute cerebral infarction have significantly effects,which is safe and reliable.