Comparison of gatifloxacin and fleroxacin on respiractory infections

VernacularTitle:加替沙星与氟罗沙星治疗呼吸系统感染的疗效比较
Author: Juan HU
Publication Type:Journal Article
Keywords: Respiractory infections; Gatifloxacin; Fleroxacin
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(6):832-833
CountryChina
Language:Chinese
Abstract: Objective To compare the clinic effects of gatifloxacin and fleroxacin on respiractory infections.Methods 160 patients of low-moderate respiractory infections were divided into observation group (80 cases) and control group (80 cases).Under common therapy,the observation group accepted gatifloxacin injection while the control group accepted fleroxacin injection.The effective rate,bacterial clearance rate and untoward effect were compared between the two groups.Results The effective rate of observation group was obviously higher than control group (88.8％ vs 72.5％,x2 =3.16,P ＜ 0.05).The bacterial clearance rate of observation group was obviously higher than control group (90.0％ vs 78.8％,x2 =6.28,P ＜ 0.05).There were 5 cases of nausea and vomiting in observation group while 3 cases of nausea and 2 cases of nausea and vomiting in control group.The diverse of untoward effect of two groups had no significance (x2 =0.03,P ＞ 0.05).Conclusion Gatifloxacin has a better clinic effect than fleroxacin.Gatifkoracin doesn't increase the untoward effect on respiractory infections.