The applicated value of Gui piperazine strange maleate in the treatment of patients with acute cerebral infarction

VernacularTitle:桂哌齐特在急性脑梗死患者治疗中的应用价值
Author: Shuxin QIAO
Publication Type:Journal Article
Keywords: Cerebral infarction; High sensitive C-reactive protein; S100B; Gui piperazine strange maleate
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(4):522-524
CountryChina
Language:Chinese
Abstract: Objective To explore the influence of Gui piperazine strange maleate on the high sensitive C-reactive protein(hs-CRP) and S100B in the serum of patients with acute cerebral infarction.Methods 90 patients with acute cerebral infarction were randomly divided into two groups,the control group(45 cases) and the treatment group (45 cases).The patients in the control group were treated through the conventional treatment,while the patients in the treatment group were treated plus Gui piperazine strange maleate.They were treated for fourteen days.The hs-CRP and S100B in the serum were detected before and after treatment.Results The total effective rates were 93.3％ in the treatment group and 84.4％ in the control group.There was a significant difference between two groups(x2 =4.0125,P ＜ 0.05).The hs-CRP and S100B were decreased after treatment in both groups (all P ＜ 0.05),and there was a significant difference between two groups after treatment (all P ＜ 0.05).Conclusion Gui piperazine strange maleate can improve acute cerebral infarction through mitigating inflammation.