Comparison of the effect of strontium-89-chlovide in the treatment of prostate cancer bone metastasis between Uygur and Han people

VernacularTitle:维吾尔族与汉族前列腺癌骨转移患者氯化锶治疗的效果比较
Author: Ximei FENG ; Shuli GUO ; Yongfang TIAN
Publication Type:Journal Article
Keywords: Racial stoks; Prostatic neoplasms; Neoplasm metastasis; Strontium; Radioisotopes
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(1):13-15
CountryChina
Language:Chinese
Abstract: Objective To analyze the effect on prostate cancer bone metastasis of Uygur and Han people treated with strontium-89-chlovide.Methods The curative effects in 36 cases of Uygur and 40 cases of Han patients with prostate cancer bone metastasis were investigated after intravenous injection with strontium-89-chloride,including palliation of pain,change of metastatic focus,level of prostate-specific antigen (PSA) and interleukin-6 (IL-6).Results After treated with strontium-89-chlovide,compared with the han patients with prostate cancer bone metastasis,the palliation rate (83.33 ％) F-PSA [(29.29 ± 8.69) μg/L] and T-PSA [(3.73 ± 1.48) ml/L] were higher,the bone metastases and the level of IL-6 were more significantly reduced of Uygur patients,and there were statistically significant (x2 =4.113,t =1.359,t =1.849,all P ＜ 0.05).Conclusion It is more effective treated with 89 SrCl-chloride for the Uygur patients with prostate cancer bone metastasis metastases than the Han patients.