Comparison of the effects of sevoflurane and disoprofol to inflammatory factors in patients received abdominal surgeries

VernacularTitle:七氟烷与丙泊酚麻醉对腹部手术患者血浆炎性因子影响的比较
Author: Weihong CAI ; Weiping ZHENG ; Yin YING
Publication Type:Journal Article
Keywords: Sevoflurane; D; Inflammatory factors
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(2):200-201
CountryChina
Language:Chinese
Abstract: Objective To explore and compare the effect of sevoflurane and disoprofol to inflammatory factors in patients received abdominal surgeries.Methods Patients with sevoflurane and disoprofol respectively were anaesthetized and detected IL-6,IL-8,IL-10 and TNF-α in their serum at T1 (when anesthesia induction),T2 (after anesthesia induction),T3 (30min after beginning of operations) and T4 (after operations).Results Compared with T1,the serum level of IL-6,IL-8,IL-10 and TNF-α increased significantly in all patients(all P ＜ 0.05) ; Compared with disoprofol group,the serum level of IL-6,IL-8 and TNF-α increased significantly (all P ＜ 0.05) ; Compared with sevoflurane group,the serum level of IL-10 increased significantly(all P ＜ 0.05).Conclusion Intravenous anesthesia with disoprofol in patients receiving abdominal operations is proper for maintenance of inflammatory balance.