Clinical analysis of purulent meningitis caused by streptococcus pneumoniae in 12 children
10.3760/cma.j.issn.1673-4912.2013.02.016
- VernacularTitle:儿童肺炎链球菌所致化脓性脑膜炎12例临床分析
- Author:
Qinling PENG
;
Hongmei LIAO
;
Jingwen TANG
;
Mei CHEN
;
Sai YANG
- Publication Type:Journal Article
- Keywords:
Streptococcus pneumoniae;
Purulent meningitis;
Children
- From:
Chinese Pediatric Emergency Medicine
2013;20(2):169-171
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics of purulent meningitis caused by streptococcus pneumoniae.Methods We studied clinical features of 12 children with purulent meningitis caused by streptococcus pneumoniae who were hospitalized from Jan 2007 to Oct 2011 in our hospital.Results Twelve children were penicillin-resistant streptococcus pneumoniae.The ages ranged from 2 months to 10 years.Nine cases(75％) were aged less than 5 years,and 5 cases(41.6％) were aged less than 2 years.All cases were with fever,and with the nervous system symptoms involvement.All cases were with complications:9 cases(75％) with septicemia,8 cases (66.7％) with pneumonia.The white blood cells,blood C-reactive protein,peripheral blood procalcitonin,erythrocyte sedimentation rate,white cells and protein in cerebrospinal fluid were mostly significantly high,sugar in cerebrospinal fluid were low significantly.Eleven cases were eventually treatmented by vancomycin plus 3rd to 4rd generations of cephalosporins antibiotics or other antibiotics.Eight cases were cured,2 cases with serious sequela,and 2 cases died.Conclusion We should attach importance to the meningitis caused by streptococcus pneumoniae.For clinical suspects pneumonia streptococcus meningitis,to given the powerful therapy by vancomycin plus the other antibiotics,as early as possible.
