Examination standards and radiological evaluation of targeted therapy for gastrointestinal stromal tumors
10.3760/cma.j.issn.1673-9752.2013.04.005
- VernacularTitle:胃肠道间质瘤靶向治疗的影像学评价与检查规范
- Author:
Xiaopeng ZHANG
- Publication Type:Journal Article
- Keywords:
Gastrointestinal stromal neoplasms;
Computed tomography;
Magnetic resonance imaging;
Diffusion weighted;
Efficacy evaluation
- From:
Chinese Journal of Digestive Surgery
2013;(4):257-261
- CountryChina
- Language:Chinese
-
Abstract:
Conventional morphological evaluation criteria cannot objectively reflect the histopathological changes of gastrointestinal stromal tumor (GIST) to targeted therapy,and therefore it is unable to adapt to the requirements of the development of personalized medicine.The emerging of Choi and subsequent joint criteria of computed tomography diagnosis provides new methods for the evaluation of the histopathological changes of GIST to targeted therapy.Positron emission tomography (PET)-standardized uptake value (SUV) and apparent diffusion coefficient (ADC) on diffusion-weighted magnetic resonance imaging (MRI) can reflect the histopathological changes of GIST to targeted therapy in the early stage through functional imaging,and provide new potential biomarkers for evaluating the efficacy.Standardized radiological examination and evaluation process are conducive to launch the personalized treatment of GIST.
