The inhibition activity of volatile oil from mappianthus iodoies on SPC-A-1 and BEL-7402 cancer cells
10.3760/cma.j.issn.1673-4246.2013.01.010
- VernacularTitle:瑶药定心藤挥发油对肺腺癌细胞和肝癌细胞的抑制活性研究
- Author:
Li ZENG
;
Rong XIANG
;
Chunyan FU
;
Wenqing YIN
- Publication Type:Journal Article
- Keywords:
Mappianthus iodoies;
volatile oil;
MTT;
Inhibition
- From:
International Journal of Traditional Chinese Medicine
2013;(1):34-36
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the inhibition activity of volatile oil from Mappianthus iodoies on SPC-A-1 and BEL-7402 cancer cells.Methods The volatile oil in Mappianthus iodoie was extracted by SFE-CO2.MTT assay was employed to test the antitumor effect of volatile oil from Mappianthus iodoies in two kinds of malignant tumor cell lines,with IC50 applied to evaluate the degree of inhibition activity.Results When the dose of volatile oil from Mappianthus iodoies was 200 μg/ml,the inhibition ratios of the tumor cell was in excess of 50%,the IC50 was 169.54,695.21 μg/ml respectively.Conclusion Volatile oil from Mappianthus iodoies extracted by SFE-CO2 has obvious inhibition activity on SPC-A-1 and BEL-7402 cancer cells.