Toll-like receptors and cancer
10.3760/cma.j.issn.1673-422X.2013.03.002
- VernacularTitle:Toll样受体与癌症研究进展
- Author:
Xiaojing WANG
;
Guiling LIANG
;
Junfu WANG
;
Xiaoqun XU
- Publication Type:Journal Article
- Keywords:
Inflammation;
Neoplasms;
Epithelium;
Toll-like receptor
- From:
Journal of International Oncology
2013;(3):166-169
- CountryChina
- Language:Chinese
-
Abstract:
Toll-like receptor (TLR) is an important pattem recognition receptor (PRR) which partici pates in innate immunity and regulates adaptive immunity.TLR can be expressed in immune cells and malig nant tumors recognize conservative molecular structure,mediate response of inflammation,tissue injury and repair,which plays an important role in the process of tumor.Research results about some molecules and signal pathways of TLR demonstrate that it can act anti or pro-tumor dual functions,which has an extensive prospects in prevention and treatment of tumor.
