Aldo-keto reductase superfamily and lung cancer
10.3760/cma.j.issn.1673-422X.2013.01.013
- VernacularTitle:醛酮还原酶超家族与肺癌
- Author:
Lina ZHANG
;
Wentao YUE
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Neoplastic processes;
Drug resistance;
Aldo-keto reductase superfamily
- From:
Journal of International Oncology
2013;(1):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Aldo-keto reductase reductase (AKR) superfamily is NADPH-dependent oxidoreductase.As a rate-limiting enzyme in polyols metabolic pathway,the activation or inactivation of AKR involves in neoplastic process of lung cancer with the metabolism of environment toxic.AKR is related to drug resistance of chemotherapy,which will be the prognostic factor of lung cancer.
