LATS2 gene and tumor
10.3760/cma.j.issn.1673-422X.2013.01.001
- VernacularTitle:LATS2基因与肿瘤
- Author:
Yanru ZHANG
;
Zhen YU
;
Lugui QIU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Signal transduction;
Gene expression
- From:
Journal of International Oncology
2013;(1):3-5
- CountryChina
- Language:Chinese
-
Abstract:
LATS2-gene,as one homolog of LATS tumor suppressor family,plays an important role in the control of cell cycles and tumor development through Hippo pathway,p53 gene and Ras-ERK signal transduction.Once an aberrant expression of LATS2 in cell to happen,it may lead to the tumor occurrence.