Age-related white matter changes: Imaging, risk factors and clinical significance
10.3760/cma.j.issn.1673-4165.2013.02.009
- VernacularTitle:年龄相关性脑白质改变:影像学、危险因素和临床意义
- Author:
Huan ZHAO
;
Liqiong CAO
;
Jia FU
- Publication Type:Journal Article
- Keywords:
Cerebral Small Vessel Diseases;
Leukoaraiosis;
Age Factors;
Magnetic Resonance Imaging;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2013;(2):122-127
- CountryChina
- Language:Chinese
-
Abstract:
Age-related white matter changes are considered as a manifestation of arteriolosclerotic small vessel disease and are associated with advanced age and vascular risk factors.White matter changes have been recognized as one of the manifestations of cerebral small vessel disease.They are the pathological basis of cognitive impairment and functional loss in the elderly.Studies have shown that when white matter changes develop to a certain extent,there will be many clinical symptoms,including cognitive impairment,dementia,depression,gait disturbances,and urinary incontinence,and they are associated with the increased risks of stroke and death.
