Effect of IL-10 in tumor
10.3760/cma.j.issn.1673-422X.2013.03.006
- VernacularTitle:IL-10在肿瘤中的作用
- Author:
Jian ZHOU
;
Lei TAO
- Publication Type:Journal Article
- Keywords:
Interleukin-10;
Neoplasms;
Suppressor factors,immunologic;
Immune-stimulating
- From:
Journal of International Oncology
2013;(3):181-184
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-10 (IL-10) is an immuno-regulatory cytokine,which is well known for its immunosuppressive function.IL-1O can act on a variety of immune cell subsets and play an immunosuppressive effect through a variety of ways.It plays an important role in the tumor immune escape.Recent studies show that IL-10 also has an immune-stimulating function,which is presumably a pluripotent cytokine.This paper will combine the latest literature to summary the positive and negative regulatory roles of IL-10,mediation ways in the tumor and the relationships with prognosis.
