Detection of the tumor markers in patients with gastric precancerous lesions
10.3760/cma.j.issn.1673-422X.2013.02.017
- VernacularTitle:胃癌癌前病变相关标志物的检测
- Author:
Zhongjuan LIU
;
Xinqi CHENG
;
Zijian GUO
;
Lina ZHAO
;
Ling QIU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Gastritis,atrophic;
Pepsinogen A;
Pepsinogen B;
Gastrins;
Helicobacter pylori
- From:
Journal of International Oncology
2013;(2):134-137
- CountryChina
- Language:Chinese
-
Abstract:
It is confirmed that chronic atrophic gastritis (CAG) caused by Helicobacter pylori is the main cause of gastric precancerous lesions.CAG is also the key determinant in gastric cancer risk assessment,which affects pepsinogen and gastrin-17 secretion.Most of the gastric cancer patients have poor prognosis,and non-invasive tools for gastric cancer screening and diagnosis are lacking.Therefore,the early detection of gastric cancer in order to reduce the disease mortality is necessary.Pepsinogen and gastrin-17 are biomarkers of gastric mucosa and gastric antra.The serological testing for the stomach-specific biomarkers offers the possibility to know preneoplastic gastric mucosal conditions.
