Application of pemetrexed for the treatment of non-small-cell lung cancer
10.3760/cma.j.issn.1673-422X.2013.02.014
- VernacularTitle:培美曲塞在非小细胞肺癌治疗中的应用
- Author:
Jun LI
;
Xiangying XU
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Radiotherapy;
Pemetrexed
- From:
Journal of International Oncology
2013;(2):123-126
- CountryChina
- Language:Chinese
-
Abstract:
Pemetrexed is a novel antifolate which is approved in the USA and Europe for the treatment of non-small-cell lung cancer (NSCLC).Researches reveal that pemetrexed enhances radiation-induced cell inactivation.A series of clinical trials of pemetrexed combined with radiotherapy for NSCLC also demonstrated that pemetrexed provides similar efficacy with lower toxicity and better tolerability than other third-generation chemotherapy drugs.
