Applications of induced pluripotent stem cell in cancer therapy

VernacularTitle:诱导性多能干细胞在肿瘤治疗中的应用
Author: Zhiqing ZHANG ; Qinghua ZHAO
Publication Type:Journal Article
Keywords: Cell differentation; Neoplasms; Induced pluripotent stem cells
From: Journal of International Oncology 2013;(2):96-99
CountryChina
Language:Chinese
Abstract: Induced pluripotent stem cells (iPSCs) are derived from differentiated somatic cells through reprogramming in vitro.Similarly to embryonic stem cells (ESCs),iPSCs have the ability of unlimited selfrenewal and multiple differentiation potential.But they are without the constraints of immunology and ethics and acquire conveniently.Patient-specific iPSCs provide an invaluable resource for disease modeling,drug discovery,regenerative therapy,immune therapy and cellular delivery vehicle in cancer therapy.Nowadays,the application of iPSCs technology has made some progress in the treatment of tumors.