Roles of apoptosis in normal and tumor microenvironment
10.3760/cma.j.issn.1673-422X.2013.02.004
- VernacularTitle:细胞凋亡在正常和肿瘤组织微环境中的作用
- Author:
Shaoting DONG
;
Hongli YANG
;
Shuang WANG
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Neoplasms;
Macrophages;
Tumor microenvironment
- From:
Journal of International Oncology
2013;(2):92-95
- CountryChina
- Language:Chinese
-
Abstract:
Apoptosis is the autonomous death of cells,which is controlled by the genes and to maintain the homeostasis of the body.Apoptosis is the important mechanism in the cell's growth and development.Recent studies have found that apoptosis can affect the neighboring cells physiological process in microenvironment through directly contact or release a series of regulatory factor,which plays an important roles in the construction of tumor microenvironment.Therefore,understanding the roles of apoptosis in the normal and tumor microenvironment has great significance for further study the pathogenesis,prevention and treatment of tumor.