Endostatin in the treatment of non-small cell lung cancer
10.3760/cma.j.issn.1673-422X.2013.01.015
- VernacularTitle:血管内皮抑制素在非小细胞肺癌中的应用
- Author:
Lei ZHANG
;
Jianyu XU
;
Xiangying XU
- Publication Type:Journal Article
- Keywords:
Endostatins;
Carcinoma,non-small-cell lung;
Radiotherapy;
Drug therapy
- From:
Journal of International Oncology
2013;(1):50-53
- CountryChina
- Language:Chinese
-
Abstract:
Endostatin is a novel anti-angiogenic drug which through multiple pathway inhibits vascular endothelial growth factor expression,to achieve the purpose of the inhibition of tumor angiogenesis.The drug in the treatment of non-small cell lung cancer in pre-clinical study and clinical application show that:used alone have anti-tumor effect; combined with radiotherapy and chemotherapy can obtain short-term curative effect,and does not increase treatment related toxicity.The adverse effect of the drug is mild and can be well tolerated.
