Research progress on Klotho gene in tumors
10.3760/cma.j.issn.1006-9801.2013.01.025
- VernacularTitle:Klotho基因在肿瘤中的研究进展
- Author:
Jingchao CAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Gene,Klotho;
Anti-tuomr gene
- From:
Cancer Research and Clinic
2013;(1):67-69
- CountryChina
- Language:Chinese
-
Abstract:
Klotho gene is a new gene found in the 20 century,which has a anti-aging function.Researchers people find that its expression in some tumors is down-regulated,such as in gastric cancer,lung cancer,breast cancer,cervical cancer,skin cancer,bladder cancer,colon cancer and so on.The ability of tumor' s replication and invasion could be inhibited through increasing the expression of Klotho gene,even be trended to apoptosis.So that the Klotho gene may be a new gene which has a anti-tumor function.