Sulfony lureas and ischemic stroke
10.3760/cma.j.issn.1673-4165.2013.01.012
- VernacularTitle:磺脲类药物与缺血性卒中
- Author:
Wei LI
;
Jiyang XU
- Publication Type:Journal Article
- Keywords:
Sulfonylurea Receptor;
Stroke;
Brain Ischemia;
Potassium Channels;
Diabetes Mellitus
- From:
International Journal of Cerebrovascular Diseases
2013;(1):65-68
- CountryChina
- Language:Chinese
-
Abstract:
Sulfonylureas are one of the major oral drugs for the treatment of type 2 diabetes mellitus.Studies in recent years have shown that such drugs have the effect of independent of reducing blood sugar on ischemic stroke.This effect is mainly associated with the combination of sulfonylurea receptor 1 (SUR1) to regulate of ATP-sensitive non-selective cation channels.