Applications of molecular diagnostics techniques in clinical microbiology laboratory
10.3760/cma.j.issn.1009-9158.2013.02.004
- VernacularTitle:分子诊断技术在临床微生物学检验中的应用
- Author:
Changgui SUN
;
Jun CHENG
- Publication Type:Journal Article
- Keywords:
Molecular diagnostic techniques;
Polymerase chain reaction;
Sequence analysis,DNA
- From:
Chinese Journal of Laboratory Medicine
2013;(2):109-112
- CountryChina
- Language:Chinese
-
Abstract:
Applications of molecular diagnostics in clinical microbiology laboratory were introduced in the article,including nucleic acid hybridization,nucleic acid amplification,DNA sequencing,gene chips and mass spectrometry.Molecular diagnostic techniques provide major tools for rapid diagnosis of infectious diseases,molecular epidemiology investigation,rapid identification of microbial pathogens and the study of the pathogenicity and antibiotics resistance.The application of these new technologies,as the complement of traditional culture methods,increases sensitivity,accuracy and diagnostic efficiency of assays.
