Characteristics of esophageal motility of different types of achalasia patients by high resolution manometry
10.3760/cma.j.issn.0254-1432.2013.02.003
- VernacularTitle:应用高分辨率测压研究不同亚型贲门失弛缓症患者的食管动力学特点
- Author:
Ling ZHANG
;
Han LIN
;
Yangbei ZHU
;
Xingang SHI
;
Luowei WANG
;
Jie CHEN
;
Duowu ZOU
- Publication Type:Journal Article
- Keywords:
Esophageal achalasia;
Manometry;
Kinetics
- From:
Chinese Journal of Digestion
2013;(2):84-87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the dynamic changes in achalasia patients by using high resolution manometry (HRM).Methods Twenty-four achalasia patients were enrolled for HRM examination and typing.The esophageal pressure of patients with different subtypes was analyzed.Chi-square test was used for count data analysis.Two independent samples t-test was used for measurement data.Results Among twenty-four achalasia patients,five patients were type Ⅰ and maledominated,18 patients were type Ⅱ and female was more than male,and only one male patient was type Ⅲ.The frequency of weight loss in type Ⅰ was higher than that of type Ⅱ (x2 =6.97,P=0.008).The frequency of chest pain and food reflux in type Ⅰ was higher than that of type Ⅱ (both P>0.05).The average distance from the nares to the upper edge of the lower esophageal sphincter (LES) with the electrode successfully inserted into the stomach was (44.9±3.3) cm and to the lower edge of the LES was (48.0±3.2) cm.The average LES length was (3.1 ±0.7) cm,average intraabdominal LES length was (2.1 ±0.5) cm.The average LES resting pressure was (34.6 ± 13.8) mm Hg (1 mm Hg =0.133 kPa) and the integrated relaxation pressure (IRP) was (31.1 ± 12.0) mm Hg.Conclusion Esophageal manometry is the golden standard for achalasia diagnosis,and HRM may be a simple,direct viewing and accurate method for accessing esophageal motor function.