Comparison of adverse effect between Cinepazide Maleate and low Molecular Dextran injection after digital replantation surgery
10.3760/cma.j.issn.1001-2036.2013.01.010
- VernacularTitle:马来酸桂哌齐特注射液与低分子右旋糖酐应用于断指再植患者不良反应的比较
- Author:
Yinlan YANG
;
Zhuyan HUANG
;
Jinling WANG
;
Ziqing ZHANG
- Publication Type:Journal Article
- Keywords:
Cinepazide Maleate injection;
Low molecular weight dextran;
Digital replantation;
Adverse effect
- From:
Chinese Journal of Microsurgery
2013;(1):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective Comparing the clinical effect between Cinepazide Maleate and low Molecular weight Dextran,to the one which is more effective,safer and less unhealthy to patients after digital replantation.Methods From April 2010 to April 2012 in our hospital during single finger replantation patients,the observation group 120 cases of postoperative to Cinepazide Maleate injection 320mg/d intravenous drip,the control group of 120 cases treated with low Molecular Dextran 500ml/d IVGTT.Results The effective rate of observe group and control group was 96.67％ and 92.50％,respectively.The difference between the two groups was too small to have statistically significant difference (P ＞ 0.05),but the adverse effect of treatment group was only 5.8％,much lower than 14.17％ in control group however with the statistically significant difference (P ＜0.05).Conclusion Cinepazide Maleate Injection and low Molecular weight Dextran both have apparent effect in patients after digital replantation surgery.Both of them significantly improved microcirculation,enhanced the survival rate of replantation.However Cinepazide Maleate injection has fewer adverse effects,which is one of idea auxiliary medicine and deserved more extensive clinic application in currently microsurgery.
