The endoscopic features of gastric low-grade intraepithelial neoplasia with carcinomatous transformation
10.3760/cma.j.issn.1007-5232.2013.01.010
- VernacularTitle:胃低级别上皮内瘤变潜在恶变风险的内镜表现分析
- Author:
Bo HOU
;
Jia YAO
;
Zhifeng WANG
;
Xing CHEN
- Publication Type:Journal Article
- Keywords:
Low-grade intraepithelial neoplasia;
Endoscopic forceps biopsy;
Endoscopic mucosal resection;
Endoscopic submucosal dissection
- From:
Chinese Journal of Digestive Endoscopy
2013;(1):33-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study aimed to evaluate the potential predictive factors for carcinomatous transformation of gastric low-grade intraepithelial neoplasia (LGIEN) on the basis of endoscopic features.Methods The study involved 312 gastric LGIENs that were histologically confirmed by endoscopic forceps biopsy (EFB) between May 2004 and September 2010,and then removed by endoscopic mucosal resection or endoscopic submucosal dissection were enrolled in this study.According to EMR/ESD postoperative pathological findings,they were divided into LGIEN group and the HGIEN group,and compared their endoscopic characteristics.Results There were not significant different between the two group,as the mean age、gender the diameter of the lesions、lesion sites and surface nodularity.The diameter of the lesions was 14.6 ± 8.2 mm in the LGIEN group and 22.0 ± 0.55 mm in the HGIEN group (P ＜ 0.05).42 of 69 gastric adenomas (60.9％)larger than 20 mm in diameter showed HGIEN (P ＜ 0.05).Hyperemia and mucosal ulceration were significant differences in the two groups.Conclusion The LGIEN lesions with these endoscopic characteristics,such as size (＞ 2 cm),surface hyperemia,ulceration should be considered for EMR/ESD.
