A comparative study of cost-effectiveness between two curative means for treating early gastrointestinal carcinoma or precancerous lesions: endoscopic submucosal dissection (ESD) vs traditional surgery
10.3760/cma.j.issn.1007-5232.2013.01.006
- VernacularTitle:消化道早癌及癌前病变内镜下切除与外科手术切除的效价比对比研究
- Author:
Xi SUN
;
Xiuli ZHANG
;
Zhongsheng LU
;
Qiyang HUANG
;
Yanqing LI
;
Yunsheng YANG
- Publication Type:Journal Article
- Keywords:
Digestive system neoplasms;
Precancerous conditions;
Endoscopic submucosal dissection;
Traditional surgery;
Cost-Benefit analysis
- From:
Chinese Journal of Digestive Endoscopy
2013;(1):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the cost-effectiveness between endoscopic submucosal dissection (ESD) procedure and traditional surgery for the treatment of early gastrointestinal cancer or precancerous lesions.Methods A total of 866 early GI cancer/precancerous patients who had been admitted to Chinese PLA General hospital and Qilu hospital were included in this study.The medical records of all 866 patients were reviewed.Patients were divided into ESD group and traditional surgery group.Parameters of each patient,such as time of hospitalization,total treatment cost and incidence of complications,were documented and later compared in detail.Results A total of 607 patients were included in the ESD group and 259 in the traditional surgery group.There was no statistical difference in complete resection rate between the two groups (93.1% vs 93.0%,P > 0.05).The ESD group showed a shorter mean hospitalization time (d)(13.01 vs 18.88,P < 0.05) and lower treatment cost (RMB) than the traditional surgery group (22932.17 vs 57993.88,P < 0.05).The incidence of hemorrhage and perforation for each group were 3.63% and 3.10% respectively,which were not significantly different (1.98% vs 3.01%,P > 0.05; 2.80% vs 1.16%,P > 0.05).Conclusion ESD and surgery are both effective for early gastrointestinal cancer/precancerous lesions therapy,but ESD procedure is superior to surgery in terms of hospitalization time and expediture.