The application of serum procalcition in early diagnosis of nosocomial infection in severe cerebral injury
10.3760/cma.j.issn.1008-6706.2013.02.034
- VernacularTitle:降钙素原在重型颅脑损伤患者医院感染早期诊断中的应用
- Author:
Huifeng YUAN
;
Hongxing ZHAO
- Publication Type:Journal Article
- Keywords:
Procalcition;
In-hospital infectionl;
C-reactive protein;
White blood cell
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(2):237-239
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical value of serum procalcition(PCT) in early diagnosis of nosocomial infection in severe cerebral injury.Methods 58 patients with severe cerebral injury needing ICU monitoring were enrolled.Levels of serum PCT and C-reactive protein(CRP) and white blood cell(WBC) and nosocomial infection when entering ICU or on days 3 were observed.Results There were not difference in level Serum PCT when entering ICU in infection group compared with non-infection group(P ＞ 0.05).Serum PCT increeassd remarkably when entering ICU on days 3 in infection group as compared with non-infection group,the difference was significant (t =5.44,P ＜ 0.01).There were not difference in CRP and WBC level when entering ICU or on days 3 (all P ＞ 0.05).Conclusion Detection of serum PCT helps diagnosis early nosocomial infection in patients with severe cerebral injury.It is suggested that antibiotics should be chosen early in patients with obviously increased PCT,control abuse of antibiotics contributes to reduce incidence of drug resistance and mortality.
