Study on three-dimensional conformal radiotherapy for 81 patients with primary hepatic carcinomas

VernacularTitle:三维适形放疗治疗原发性肝癌81例
Author: Donghui LU ; Liting QIAN ; Zhenle FEI
Publication Type:Journal Article
Keywords: Hepatic neoplasms; Three-dimensional conformal radiotherapy; Result
From: Cancer Research and Clinic 2013;(2):115-118
CountryChina
Language:Chinese
Abstract: Objective To analyse the efficacy of three-dimensional conformal radiotherapy(3D-CRT)for hepatic carcinomas.Methods 81 patients with advanced hepatic carcinoma were treated at every turn of 200-400 cGy to a total dose of 4800-5500 cGy.Average-dose was 4580 cGy.Following up time was 225 monthes.Recent effect was evaluated according to WHO tumor evaluation standard.Results 81 patients accomplished the treatment.The local response rate was 82.7 ％(67/81)after treatment with 21 cases CR,46 cases PR.The 1,2 year overall survival rates were 43 ％,26 ％.In the multivariate analysis,the recent effect,the total dose,metastasis,clinical staging,the diameter of the tumors and Child grade presages had statistical significance for overall survival(all P ＜ 0.05).Conclusion 3D-CRT is preferable therapeutic action for primary hepatic carcinomas and can prolong the survival term.