Twenty cases of cerebral venous sinus thrombosis presented as isolated intracranial hypertension

Yang LU; Shilei Cui; Rong Yan; Houliang Sun; Zhenchang Wang; Xiaojun Zhang

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Twenty cases of cerebral venous sinus thrombosis presented as isolated intracranial hypertension

VernacularTitle:表现为单纯性颅内压增高的颅内静脉窦血栓形成20例患者的临床和影像学特点
Author: Yang LU ; Shilei CUI ; Rong YAN ; Houliang SUN ; Zhenchang WANG ; Xiaojun ZHANG
Publication Type:Journal Article
Keywords: Sinus thrombosis,intracranial; Intracranial hypertension; Magnetic resonance imaging
From: Chinese Journal of Neurology 2013;(2):112-116
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical and image features of cerebral venous sinus thrombosis (CVST) presented as isolated intracranial hypertension.Methods The medical records of patients with diagnosis of CVST presented as isolated intracranial hypertension were reviewed.Clinical features and imaging data were retrospectively analyzed.Results Twenty cases of CVST were included,all these patients were clinically presented as isolated intracranial hypertension.The male to female ratio was 13:7,and the average age was (38.3 ± 11.7) years old.None of the patients was obesity.The visual acuity was lower than 0.1 in 42.5％ (17/40)of the eyes.Possible risk factors relevant to CVST were found in 11 cases (55％),including head trauma for 4 cases,autoimmune disease for 2 cases,and other causes of single case including spontaneous abortion,phlebitis,otitis media postoperative,trigeminal nerve microvascular decompression surgery and obstructive sleep apnea syndrome.Image analysis showed that lateral sinus thrombosis was involved in 85％ (17/20) of the patients,while superior sagittal sinus was involved in 35％ (7/20),and 65％ (13/20) of the patients were isolated lateral sinus thrombosis.Conclusions Young male predominance is found in CVST patients which presented as isolated intracranial hypertension but severe visual function loss.Risk factors such as head trauma are commonly found in these patients.Most of the patients are isolated lateral sinus thrombosis,with lateral sinus narrowing as the most common abnormal findings in magnetic resonance venogram.