Clinical significance of changes in maximal expiratory flow in 50 % and 25 % vita l capacity before and after bronchodilator reversibility testing in asthmatics
10.3760/cma.j.issn.1671-7368.2013.02.027
- VernacularTitle:哮喘患者支气管舒张试验前后50%和25%肺活量时最大呼气流速的临床意义
- Author:
Hanxiang NIE
;
Min LIU
;
Xuhong DING
;
Yi HUANG
;
Suping HU
- Publication Type:Journal Article
- Keywords:
Asthma;
Respiratory function tests
- From:
Chinese Journal of General Practitioners
2013;(2):145-146
- CountryChina
- Language:Chinese
-
Abstract:
To explore the clinical significance of changes in maximal expiratory flow in 50% and 25% vital capacity (Vmax50% & Vmax25%) before and after bronchodilator reversibility testing in patients with asthma.Forced expiratory volume in one second (FEV1),Vmax50% and Vmax25% were measured before and after bronchodilator reversibility testing in 118 patients with asthma and 82 with chronic obstructive pulmonary disease (COPD).The rate of positive reversibility in Vmax50% was significantly higher than that in FEV1 in 118 asthmatics (x2 =7.995,P =0.007).The rates of positive reversibility in Vmax50% and Vmax25% were significantly higher in asthmatics than those in COPD patients (x2 =9.335,P =0.009).