Treatment of ectopic pregnancy by two dosages of mifepristoned plus methotrexate
10.3760/cma.j.issn.1671-7368.2013.01.026
- VernacularTitle:米非司酮两种方案联合甲氨蝶呤治疗异位妊娠效果比较
- Author:
Cuimei LI
;
Zhiping DENG
;
Bin ZHU
- Publication Type:Journal Article
- Keywords:
Mifepristone;
Pregnancy,ectopic
- From:
Chinese Journal of General Practitioners
2013;(1):61-63
- CountryChina
- Language:Chinese
-
Abstract:
The clinical efficacy of two dosages of mifepristone plus methotrexate (MTX) in the treatment of ectopic pregnancy was compared.One hundred and fifty patients with ectopic pregnancy patients were stratified randomly into 200 mg's single oral group (n =77) and 150 mg graded oral group (n =73).The results showed that,when the Fernandez scores ≤ 12 points,the difference of treatment success rate was not statistically significant (98％ vs 100％,P ＞0.05) ; and when ＞ 12 points,two groups had statistical significance difference (10/13,3/11,P ＜ 0.05).The incidence of gastrointestinal adverse reactions was statistically significant between two groups (P ＜ 0.05).However,the number of leucopenia,the time of hCG back to normal and average length of hospital stay were not statistically different(P ＞0.05).
