Early clinical efficacy of alendronate sodium on residual pain after vertebral angioplasty for osteoporotic vertebral compression fractures
10.3760/cma.j.issn.0254-9026.2013.03.006
- VernacularTitle:阿仑膦酸钠治疗骨质疏松性脊柱压缩性骨折椎体成形术后残余疼痛的早期疗效观察
- Author:
Xiaofang DING
;
Yuanli WANG
;
Shutang WANG
;
Hailin XU
- Publication Type:Journal Article
- Keywords:
Osteoporosis fractures;
Vertebroplasty;
Pain
- From:
Chinese Journal of Geriatrics
2013;(3):260-262
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the early clinical efficacy of alendronate sodium on residual pain after vertebral angioplasty for osteoporotic vertebral compression fractures.Methods By drug single treatment method,a total of 30 elderly patients with residual pain after vertebral angioplasty for osteoporotic vertebral compression fractures were included.Patients were randomly divided into 2 groups:the treatment group and the control group.All patients were given calcium carbonate D3 treatment,and the treatment group was given alendronate sodium treatment additionally.6 weeks after the treatment,visual analogy score (VAS) was used for the evaluation of pain relief.Results All patients were followed up for 6 weeks.At the end of follow-up,the rates of pain relief were 86.8％ in treatment group and 13.2％ in control group.There was a significant difference in visual analogy scores between the treatment group and the control group[(0.51±0.32),(1.59±1.21) ; t=3.4,P＜0.001],which showed the degree of pain relief was higher in the treatment group than in control group.Conclusions Alendronate sodium is effective and reliable for the treatment of residual pain after vertebral angioplasty for osteoporotic vertebral compression fractures.This study provides the scientific reference for the treatment and research of residual pain after vertebral angioplasty for osteoporotic vertebral compression fractures.
