Effect of enteral nutrition on the glucose and fat metabolism in elderly patients with metabolic symdrome and nonalcoholic fatty liver disease

VernacularTitle:肠内营养支持治疗对老年代谢综合征合并非酒精性脂肪肝患者的临床意义
Author: Wei WANG ; Le XU
Publication Type:Journal Article
Keywords: Enteral nutrition; Metabolic syndrome; Fatty liver
From: Chinese Journal of Geriatrics 2013;(1):80-84
CountryChina
Language:Chinese
Abstract: Objective To observe the effects of enteral nutrition on the glucose and fat metabolism in elderly patients with metabolic symdrome (MS) and nonalcoholic fatty liver disease (NAFLD).Methods The 109 patients with MS and NAFLD were randomized into enteral nutrition(EN)(n=55)and total parenteral nutrition(TPN) (n=54) group.The EN patients received aggressive enteral nutrition therapy,the TPN patinets got the treatment of total parenteral nutrition.The body mass index (BMI),liver function,blood glucose,blood liquid and hepatic ultrasonography were observed in two groups.Results After treatment of 2 monthes,the values of BMI,TG and LDL-C were decreased,2 hBG,HbA1c,ALT,AST and BIL were significant improved in enteral nutrition group in comparison with pretherapy (P＜0.05),while not significantly different in total parenteral nutrition group(P＞0.05).There were 55.6 ％ (10/18) patients changing from middle fatty liver mild fatty liver in enteral nutrition group,while only 46.2％ (6/13) in TPN group (P＞0.05).Conclusions EN support is superior to TPN in improving the glucose and fat metabolism in elderly patients with MS and NAFLD.