Analysis of saponins in Panax notoginseng by UPLC-LTQ-Orbitrap MS/MS.
- Author:
Wen XU
;
Xiaohui QIU
;
Jing ZHANG
;
Dayuan ZHU
;
Yiming YANG
;
Chuanjian LU
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2012;47(6):773-8
- CountryChina
- Language:Chinese
-
Abstract:
A method for qualitative analysis of constituents in Panax notoginseng by UPLC-LTQ-Orbitrap mass spectrometry was established. Based on the high-resolution mass information, MS/MS fragmentation behaviors and chemical components from literatures, 43 compounds were identified or tentatively characterized. New type saponin aglycone, combined with malonyl-substituted and acetyl-substituted saponins were discovered and plausibly identified in this study. This work could be helpful for the quality control and further phytochemical studies of Panax notoginseng, and provided a good example for the analysis of chemical constituents in traditional Chinese medicine.
