Applied value of 320-slice CT perfusion examination in ischemic-type biliary lesions after liver transplantation
10.3760/cma.j.issn.0254-1785.2012.10.010
- VernacularTitle:320排CT灌注检查在肝移植后肝动脉狭窄合并缺血性胆道病变中的应用价值
- Author:
Yuan FANG
;
Xiaochun MENG
;
Jie QIN
;
Jiansheng ZHANG
;
Peiyi XIE
;
Li QUAN
;
Hong SHAN
- Publication Type:Journal Article
- Keywords:
Liver transplantaton;
Bile duct diseases;
Ischemia;
Hepatic artery stenosis;
Tomography,X-ray computed;
Perfusion
- From:
Chinese Journal of Organ Transplantation
2012;(10):611-614
- CountryChina
- Language:Chinese
-
Abstract:
Objective Using CT perfusion (CTP) technique,to investigate the graft perfusion changes in patients with hepatic artery stenosis (HAS) with or without ischemic-type biliary lesions (ITBL) after orthotopic liver transplantation (OLT).Methods Thirteen recipients with HAS received CTP scan of the liver,including 8 with ITBL and 5 without ITBL.For all patients,the diagnosis of HAS was made by CTA,and the diagnosis of ITBL by percutaneous transhepatic cholangiography.CT perfusion indices were obtained,including hepatic artery perfusion (HAP),portal vein perfusion (PVP),total liver perfusion (TLP) and hepatic perfusion index (HPI).Results Of the 13 patients with HAS,mean HAP in patients with and without ITBL was 59.8 and 35.1 ml·min-1 ·100 ml-1 (P =0.021,two-tailed paired Student t test) ; mean PVP was 125.4 and 166.2 ml·min-1·100 m1-1 (P =0.016) ; mean TLP was 185.2 and 201.3 ml· min-1 · 100 ml-1 (P =0.306) ; and mean HPI was 33.6 and 18.2 (P =0.005),respectively.Conclusion Using CTP technique,liver perfusion changes were reflected by measuring CTP indices noninvasively.Compared to those without ITBL in this study,HAP and HPI in patients with ITBL were higher and PVP was lower,which may be contributed to biliary inflammation.
