Surgical treatment of hilar cholangiocarcinoma
10.3760/cma.j.issn.1007-631X.2012.12.002
- VernacularTitle:肝门部胆管癌的外科治疗
- Author:
Xinglei QIN
;
Min LU
;
Zuoren WANG
;
Meng JIA
;
Lin WANG
;
Yunfeng ZHANG
;
Ke LI
;
Huanzhou XUE
- Publication Type:Journal Article
- Keywords:
Common bile duct neoplasms;
Biliary tract surgical procedures;
Prognosis
- From:
Chinese Journal of General Surgery
2012;(12):966-969
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and the prognosis after surgical treatment for hilar cholangiocarcinoma (HCC).Methods The surgical therapy and follow-up result were retrospectively analyzed on 98 cases of hilar cholangiocarcinoma admitted into our hospital from January 1995 to January 2005.Differences between groups were evaluated using Chi-square analysis or Student t-test according to the data type.Survival rate was calculated with Kaplan-Meier method,and using the log-rank test.Results Among 98 patients,83 patients underwent surgical treatment (radical resection in 33,palliative resection in 16,and nonresectional internal or external bile duct drainage in 34),15 patients underwent conservative therapy.The 1-,3-,5-year survival rates were 79%,42%,and 17% in the resection group and 88%,54%,and 24% in the radical resection group,respectively.The 1-,3-year survival rates were 55%,and 9% in palliative resection group,respectively,and none of the patient survived for over 5 years.There were significant differences in the survival rate among the radical resection group and the palliative resection group (log-rank test,P < 0.001).Conclusions Radical resection improves the prognosis of hilar cholangiocarcinoma.