Effect of extracorporeal circuit on the concentration of sufentanil the priming solution

VernacularTitle:体外循环回路对预充液舒芬太尼浓度的影响
Author: Fang LI ; Yonghui DI ; Jingui GAO ; Shiwei YAN
Publication Type:Journal Article
Keywords: Extracorporeal circulation; Sufentanil
From: Chinese Journal of Anesthesiology 2012;(9):1085-1087
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of extracorporeal cjrcuit on the concentration of sufentanil the priming solution.Methods The extracorporeal circuit (ECC) of Xi-jing-90 type (group A) was used in the study,while incontrol group (group B) a glass container was used.The ECC and glass container were filled with priming solution (succinylated Gelatin 1000 ml + lactated Ringer's solution 1000 ml).Sufentanil 15 μg was then added to the priming solution (the final concentration was 7.5 ng/ml).The priming solution was circulated in the closed ECC or stirred in the glass container.The concentration of sufentanil in the priming solution was determined at 3,5,10,20,30,40,50,60,70,80 and 90 min after addition of sufentanil by gas chromatography.Results The sufentanil concentration in.the priming solution decreased in group A at the different time points respectively as compared with group B (P ＜ 0.05).Conclusion Sufentanil can significantly be absorbed by the extracorporeal circuit.