Clinicopathologic analysis of prostate biopsy in men younger than 50 years of age with prostate-specific antigen 4-10 μg/L
10.3760/cma.j.issn.1000-6702.2012.11.011
- VernacularTitle:＜50岁PSA4～10μg/L患者前列腺穿刺的临床病理特点分析
- Author:
Wei YU
;
Yunxiang XIAO
;
Xuesong LI
;
Yi SONG
;
Xinyu YANG
;
Qun HE
;
Shuqing LI
;
Gangzhi SHAN
;
Zhisong HE
;
Liqun ZHOU
;
Jie JIN
- Publication Type:Journal Article
- Keywords:
Prostate-specific antigen;
Digital rectal examination;
Biopsy,needle;
Prostatic neoplasms
- From:
Chinese Journal of Urology
2012;(11):840-842
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the prostate biopsy results in young men with age less than 50 years and with PSA 4-10 μg/L.Methods From January 2006 to December 2011,22 patients with PSA 4-10 μg/L underwent prostate biopsy for free/total PSA ≤ 0.16 (20 cases) and/or positive digital rectal examination (DRE) (4 cases).The nean age was 43 years (range,24-49 years),the mean PSA level was 7.08 μg/L (range,4.17-9.74 μg/L),the mean free/total PSA level was 0.11 (range,0.03-0.53).Radiologic suspicious lesion was founded in 13 cases.Clinicopathological data from these patients were reviewed.Results The results of the biopsy were 1 (4.5％) case of prostate cancer,2 cases (9.1％) with tuberculosis,9 cases (40.9％) with inflammation,10 cases (45.5％) with benign tissue.In 20 cases with free/total PSA ≤0.16,only 1 case was diagnosed as prostate cancer.In 4 cases with positive DRE,tuberculosis (2 cases) and inflammation (1 case) were diagnosed.Conclusions The prostate cancer detection was rare in young men less than 50 years of age with PSA 4-10 μg/L.The most common cause was prostate hyperplasia with inflammation.
