Study on influencing factors and clinical characteristic of High Intensity Focused Ultrasound ablation analgesic in middle-late stage pancreatic carcinoma

VernacularTitle:中晚期胰腺癌高强度聚焦超声消融止痛效果的影响因素和临床特征分析
Author: Huming WANG ; Dinghua ZHOU ; Shanshan DING
Publication Type:Journal Article
Keywords: Pancreatic carcinoma; High intensity focused ultrasound; Pain
From: Clinical Medicine of China 2013;(2):179-182
CountryChina
Language:Chinese
Abstract: Objective To study the influencing factors and clinical characteristic of High Intensity Focused Ultrasound(HIFU) abhtion analgesic in middle-late stage pancreatic carcinoma.Methods Seventyone cases pancreatic cancer patients underwent HIFU treatment were grouped according to the pain efficacy of related influencing factors and the data was analyzed by single factor correlation analysis.The relationship between influencing factors and analgesic effect were analyzed through the pain outcome score.Results Pain score decreased ≥50％ in advanced pancreatic cancer patients occurred in ＜60 years old,Body mass index (BMI) ＜ 22 kg/m2,tumor location in the pancreatic head and neck,tumor size of 2-5 cm,and the average power of HIFU treatment ＞ 400 W,Ductal adenocarcinoma of the tumor histological type were related to the degree of pain rehef,and the difference was statistically significant (P ＜ 0.05).And fewer complications occurred after HIFU ablation.Conclusion Analysis of the relationship between the different factors and the analgesic effect in advanced pancreatic carcinoma can be used to predict the efficacy of HIFU treatment.