Analysis of the clincal chracteristics of non-steroidal anti-inflammatory drugs caused gastrointestinal bleeding in the elderly patients
10.3760/cma.j.issn.1008-6315.2013.02.006
- VernacularTitle:老年人非甾体类抗炎药致消化道出血的临床特征分析
- Author:
Man LI
;
Zhiguang ZHANG
;
Wei LU
;
Xiuli XIA
;
Yinglan JI
- Publication Type:Journal Article
- Keywords:
The elderly;
Non-steroidal anti-inflammatory drugs;
Gastrointestinal bleeding;
Aspirin
- From:Clinical Medicine of China
2013;(2):132-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features of non-steroidal anti-inflammatory drugs (NSAIDs) caused gastrointestinal bleeding in the elderly.Methods We performed a retrospective analysis ofNSAIDs caused gastrointestinal bleeding with 308 cases admitted to Department of Gastroenterology,The Second Hospital of Tianjin Medical University.Patients were divided into elderly group(≥65 years,n =208) and young group (＜ 60 years,n =100) to make a comparative analysis of two group differences in clinical characteristics.Results The NSAIDs in the elderly taking were mainly Aspirin (55.8 ％ (116/208)),which was significantly more frequent than that of young group (37.0％ (37/100),x2 =9.517,P ＜ 0.05).There was no significant difference on the blood routine and coagulation between the two groups (P ＞ 0.05).The recent bleeding rate of the elderly group (21.2％ (44/208)) was lower than the young group (63.0％ (63/100))(x2 =52.161,P ＜0.05).The two groups had no significant difference on the history of uleer and Hp infection (P ＞ 0.05).Conclusion The clinical characteristics of NSAIDs caused gastrointestinal bleeding on the elderly were different with young or middle-aged.This infers that elderly patients need individualized treatment.
